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José L Neira Selected Research

NUPR1 inhibitor ZZW-115

1/2020ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.
1/2019Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.

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José L Neira Research Topics

Disease

17Neoplasms (Cancer)
08/2023 - 05/2002
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 08/2010
3Neoplasm Metastasis (Metastasis)
01/2023 - 09/2011
3Pancreatitis
11/2019 - 01/2018
3Adenocarcinoma
01/2019 - 01/2017
3Infections
08/2013 - 11/2009
2Carcinogenesis
08/2017 - 11/2007
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2021
1Inborn Genetic Diseases (Disease, Hereditary)
03/2019
1Breast Neoplasms (Breast Cancer)
09/2011

Drug/Important Bio-Agent (IBA)

12Proteins (Proteins, Gene)FDA Link
08/2023 - 11/2003
10Inosine Diphosphate (IDP)IBA
08/2023 - 01/2016
9Intrinsically Disordered ProteinsIBA
10/2021 - 01/2017
4EnzymesIBA
08/2023 - 03/2019
2NUPR1 inhibitor ZZW-115IBA
01/2020 - 01/2019
1CitrullineIBA
01/2023
1Protein Isoforms (Isoforms)IBA
01/2023
1arginine deiminaseIBA
01/2023
1Arginine (L-Arginine)FDA Link
01/2023
1AntigensIBA
01/2023
1Karyopherins (Importin)IBA
11/2022
1Peptides (Polypeptides)IBA
01/2021
1TropomyosinIBA
01/2021
1Nuclear Proteins (Protein, Nuclear)IBA
01/2020
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2020
1ProteomeIBA
03/2019
1Flavin-Adenine Dinucleotide (FAD)IBA
03/2019
1FlavoproteinsIBA
03/2019
1Antipsychotic Agents (Antipsychotics)IBA
01/2019
1Trifluoperazine (Stelazine)FDA LinkGeneric
01/2019
1ChromatinIBA
01/2018
1CytokinesIBA
08/2013
1ChemokinesIBA
08/2013
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
09/2011
1DNA (Deoxyribonucleic Acid)IBA
08/2010
1FlavodoxinIBA
11/2009
1Antiviral Agents (Antivirals)IBA
11/2009
1Polycomb Repressive Complex 1IBA
11/2007
1Protein Subunits (Protein Subunit)IBA
11/2007
1Tumor Protein p73IBA
05/2002

Therapy/Procedure

1Ligation
08/2023